Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Russo on bactrim ds mrsa dosage: Sulfonamide drugs were frequently used for Strep throat in the 1930s but fell out of favor approximately 10 years later when it was felt that bacterial resistance has developed. However, at least one study has proven this to be false, and sulfonamide drugs may be useful for this. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Raff on bactrim dose for mrsa: If you are normal size with normal renal function 1 double strength tablet (160/800 mgs) 3 times a day. We undertook this study to investigate whether treatment with a higher dose of trimethoprim-sulfamethoxazole (TMP/SMX) led to greater clinical resolution in patients with skin and soft tissue infections (SSTIs) caused by methicillin-resistant Staphylococcus aureus (MRSA). In patients with persistent MRSA bacteremia and vancomycin treatment failures, 5 mg/kg/dose (trimethoprim component) IV every 12 hours in combination with high dose daptomycin. If there is reduced susceptibility to vancomycin and daptomycin, sulfamethoxazole; trimethoprim may be administered as a single agent or in combination with other antibiotics. The 2014 Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections (SSTI) recommend sulfamethoxazole-trimethoprim (SMX-TMP) for purulent infections where methicillin-resistant S. aureus (MRSA) is a likely pathogen. 1 But, what dose of SMX-TMP should we be prescribing? Prophylaxis: 2 mg TMP/kg/dose PO qDay or 5 mg TMP/kg/dose twice weekly Skin/soft Tissue Infection Due to Community Acquired MRSA (Off-label) 8-12 mg TMP/kg/day PO q12hr for 5-10 days; add beta-lactam antibiotic to regimen if beta-hemolytic Streptococcus spp also suspected Many people mistake the first signs of methicillin-resistant Staphylococcus aureus (MRSA) infection for a spider bite. In fact, what appears as a small, red pimple could be the start of a. Adults: The usual adult dosage in the treatment of urinary tract infections is 1 BACTRIM DS (double strength) tablet or 2 BACTRIM tablets every 12 hours for 10 to 14 days. The recommended dosage for prophylaxis in adults is 1 BACTRIM DS (double strength) tablet daily. 12 Children: For children, the recommended dose is 750 mg/m 2 /day sulfamethoxazole with 150 mg/m 2 /day trimethoprim given orally in equally divided doses twice a day, on 3 consecutive days per week. Rx only BACTRIM™ sulfamethoxazole and trimethoprim DS (double strength) tablets and tablets USP. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim.